Project: Microphysiological Systems
Type: Standards Advancement Project
Partners: the SCB Tissue Engineering Sector Working Group
Get Involved:Standard published: additional needs TBD
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Description:
Microphysiological systems (MPS)—which include organs-on-a-chip, diseases-on-a-chip, and other interconnected cellular constructs—are an invaluable tool in the study of both healthy and diseased tissue and organ systems. MPS can also be used in the development of new drug therapies to increase the speed and accuracy of drug safety and efficacy assessments. However, this field lacks relevant standards, leading to inconsistent terminology and difficulty comparing methodology and results, which impedes understanding among product developers and slows the wide adoption of MPS as a research tool.
SCB is working with experts to advance three ASTM standards: an MPS lexicon, a best practices document for cardiac and cardiovascular MPS, and a standard on materials for MPS.
Anticipated Availability:
Terminology for MPS - Now
Cardiac MPS - Late 2023
Materials for MPS - 2025
Progress:
(learn more about the standards advancement process)
Note: Projected start dates are estimates only. Development of a standard depends on SDO timelines, which can vary.
Coordinate MPS Standards Working Group: SCB has assembled and is leading a working group for the MPS efforts.
Coordinating Standards: Each of the standard projects was accepted for development by ASTM (ASTM WK77165, New Guide for Cardiac Microphysiological Systems, and Materials for Microphysiological Systems [standard ID pending]). SCB will continue to coordinate the working group as the standards move through the ASTM development process.
Published Terminology Standard: The Standard Terminology Relating to Microphysiological Systems project was published in July 2022 as ASTM F3570-22.
Get Engaged:
To learn more about this initiative, please contact SCB.